Don't Rush to Crush 4th Edition Updates

December 2022 update: five new monographs – decitabine/cedazuridine, diroximel fumurate, gilteritinib, ripretinib and selinexor. There is new information for nirmatrelvir/ritonavir (Paxlovid) for people with enteral feeding tubes or swallowing difficulties and new information for posaconazole for people with enteral feeding tubes. There is updated advice for ibuprofen, irbesartan and lansoprazole in response to user feedback. The monographs for ertugliflozin, leflunomide, olaparib and roxithromycin have been updated to reflect changes in product availability.

June 2022 update: four new monographs –  alpelisib, amifampridine, larotrectrenib, and pentosan polysulfate. There is new information for molnupiravir for people with swallowing difficulties and updated advice for rifampicin in response to user feedback. The monographs for clozapine, dasatinib, dipyridamole and aspirin, efavirenz, maviret, phentermine, and ribavirin have been updated to reflect changes in product availability:

May 2022 update: the Bosentan monograph has been updated to correct an error in the What to do for doses less than a whole tablet section.

March 2022 update: five new medicines including two new COVID-19 treatments  – molnupiravir (Lagevrio) and nirmatrelvir plus ritonavir (Paxlovid).